| Main Title |
Studies on the Safety of DDVP for the Disinsection of Commercial Aircraft. |
| Author |
Witter, Robert F. ;
Gaines, Thomas B. ;
Short, J. Gordon ;
Sedlak, V. A. ;
Maddock., D. R. ;
|
| CORP Author |
Communicable Disease Center, Savannah, Ga. |
| Year Published |
1961 |
| Stock Number |
PB-277 612 |
| Additional Subjects |
Insecticides ;
Pesticides ;
Toxicology ;
Toxicity ;
Phosphorus organic compounds ;
Humans ;
Monkeys ;
Exposure ;
Laboratory animals ;
Experimental data ;
Aircraft ;
Concentration(Composition) ;
Cholinesterase inhibitors ;
Bioassay ;
Reprints ;
Toxic hazards ;
Toxic substances ;
DDVP insecticide
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-277 612 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
There is a need for a more effective method for the disinsection of intercontinental aircraft. A study was made of the possible toxic hazard associated with a new method of disinsection using DDVP vapour (O,O-dimethyl-2,2-dichlorovinyl phosphate) as the insecticidal agent. In these experiments, men and monkeys were exposed four times over one- or two-hour periods for a total of 4-8 hours to DDVP vapour in a simulated aircraft cabin. The concentration of DDVP was higher and the exposure periods were longer than those planned for use in disinsection. Concentrations up to 0.7 micrograms per litre of air produced no effect on the cholinesterase of men or monkeys. It was found that a concentration of DDVP of 0.9-3.5 microgram per litre of air caused a slight decrease in plasma cholinesterase of the men and the monkeys. At a DDVP concentration of 7.5-17.9 microgram per litre, monkeys exhibited a marked drop in red cell and plasma cholinesterase and showed miosis, but no other signs of poisoning. |
| Supplementary Notes |
Pub. in Bull. Wld Hlth Org., 24 p635-642 1961. |
| Availability Notes |
Included in the report, Journal Articles on Toxicology. Group 1, PB-277 586. |
| Title Annotations |
Reprint: Studies on the Safety of DDVP for the Disinsection of Commercial Aircraft, |
| PUB Date Free Form |
1961 |
| Category Codes |
6T; 6F; 57Y; 68E |
| NTIS Prices |
(Order as PB-277 586, MF A01) |
| Primary Description |
500/01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
323734508 |
| Origin |
NTIS |
| Type |
CAT |
