Main Title |
Effect of Chlorine Treatment on Infectivity of Hepatitis A Virus. |
Author |
Peterson, David A. ;
Hurley, Thomas R. ;
Hoff, John C. ;
Wolfe, Lauren G. ;
|
CORP Author |
Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL.;Municipal Environmental Research Lab., Cincinnati, OH. |
Year Published |
1983 |
Report Number |
EPA-600/J-83-001; |
Stock Number |
PB83-163451 |
Additional Subjects |
Hepatitis viruses ;
Chlorination ;
Disinfection ;
Viruses ;
Treatment ;
Monkeys ;
Laboratory animals ;
Reprints ;
Hepatitis A virus
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB83-163451 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
7p |
Abstract |
This study examined the effect of chlorine treatment on the infectivity of hepatitis A virus (HAV). Prodromal chimpanzee feces, shown to induce hepatitis in marmosets (Saguinus sp.), was clarified, and the virus was precipitated with 7% polyethylene glycol 6000, harvested and resuspended. The suspension was layered onto 5 to 30% linear sucrose gradients and centrifuged; the fractions containing HAV were dialyzed, and a 1:500,000 dilution of this preparation induced hepatitis and seroconversion in 2 of 4 marmosets. A 1:50 dilution of this preparation served as inoculum. Untreated inoculum induced overt hepatitis and seroconversion in 100% (5 of 5) of marmosets inoculated intramuscularly. |
Supplementary Notes |
Pub. in Applied and Environmental Microbiology, v45 n1 p223-227 Jan 83. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Effect of Chlorine Treatment on Infectivity of Hepatitis A Virus. |
PUB Date Free Form |
1983 |
Category Codes |
6T; 6M; 57Y; 57K |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/14 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
314724368 |
Origin |
NTIS |
Type |
CAT |