Main Title |
Use of Respiratory-Cardiovascular Responses of Rainbow Trout ('Salmo gairdneri') in Identifying Acute Toxicity Syndromes in Fish Part 3. Polar Narcotics. |
Author |
Bradbury, S. P. ;
Henry, T. R. ;
Niemi, G. J. ;
Carlson, R. W. ;
Snarski, V. M. ;
|
CORP Author |
Environmental Research Lab.-Duluth, MN. |
Publisher |
c1989 |
Year Published |
1989 |
Report Number |
EPA/600/J-89/012; |
Stock Number |
PB89-236335 |
Additional Subjects |
Toxicity ;
Fresh water fishes ;
Enzyme inhibitors ;
Cardiovascular system ;
Phenol ;
Trout ;
Intoxication ;
Tremors ;
Respiration ;
Anilines ;
Animal physiology ;
Exposure ;
Cholinesterase inhibitors ;
Reprints ;
Salmo gairdneri
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB89-236335 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
17p |
Abstract |
The physiological responses of rainbow trout to acutely lethal aqueous concentrations of the suspected polar narcotics phenol, 2,4-dimethylphenol, aniline, 2-chloroaniline and 4-chloroaniline were examined. Visible signs of intoxication included tremors that progressed to whole-organism clonic seizures, followed by general depression and respiratory-cardiovascular collapse. Tremors and seizures were usually initiated with coughs. The most striking changes in the respiratory-cardiovascular parameters for all five toxicants included elevated cough frequency (coincident with seizures), ventilation frequency and hematocrit, and depressed gill oxygen uptake efficiency, arterial pH, total arterial oxygen and total arterial carbon dioxide. The physiological responses noted were attributed to the initial muscular activity associated with seizures followed by respiratory-cardiovascular collapse. Using phenol as a model compound, these effects were found to be reversible when intoxicated fish were exposed to chemical-free water. Principal components analyses of the physiological responses demonstrated that the 11 monitored variables were highly correlated. |
Supplementary Notes |
Pub. in Environmental Toxicology and Chemistry, v8 p247-261, 1989. See also PB88-107073. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Use of Respiratory-Cardiovascular Responses of Rainbow Trout ('Salmo gairdneri') in Identifying Acute Toxicity Syndromes in Fish Part 3. Polar Narcotics. |
Category Codes |
57Y; 57Z; 57H |
NTIS Prices |
PC A03/MF A01 |
Primary Description |
600/03 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
930024484 |
Origin |
NTIS |
Type |
CAT |