| Main Title |
Environmental Assessment: Short-Term Tests for Carcinogens, Mutagens and Other Genotoxic Agents. |
| Author |
Trontell, Ann ;
Connery, Jan ;
|
| CORP Author |
Energy Resources Co., Inc., Cambridge, MA.;Environmental Research Center, Cincinnati, OH. |
| Year Published |
1979 |
| Report Number |
EPA/615/9-79/003; |
| Stock Number |
PB-300 611 |
| Additional Subjects |
Carcinogens ;
Mutagens ;
Toxicology ;
Genetics ;
Environments ;
Assessments ;
Prediction ;
Tests ;
Cells(Biology) ;
Deoxyribonucleic acids ;
Hazards ;
Trends ;
Research ;
Stategies ;
Programs ;
Utilization ;
Toxic substances ;
Genotoxins
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-300 611 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
35p |
| Abstract |
Short-term tests have been developed to serve as rapid and relatively inexpensive predictors of a chemical's potential to cause chronic effects. These tests employ bacteria, yeast, plants, insects, isolated mammalian cells and whole animals. Short-term tests can detecta chemical's genotoxicity, that is, its ability to alter a cell's genetic material (DNA). The document is organized into five sections. The first section discusses how short-term tests can contribute to hazard assessment, while the second describes the scientific basis and techniques of short-term tests. A general strategy for how short-term tests can be used to detect a chemical's potential long-term toxicity is outlined in the third section. Some program applications of short-term test research are presented in the fourth section, and the fifth section describes some of the current research activities. An overall perspective concludes the document. A glossary of technical terms is provided at the end of the document along with an appendix of technical information on specific short-term tests. |
| Supplementary Notes |
Prepared in cooperation with Health Effects Research Lab., Research Triangle Park, NC. Prepared for Environmental Research Center, Cincinnati, OH. |
| NTIS Title Notes |
Technology transfer rept.. |
| PUB Date Free Form |
Jul 79 |
| Category Codes |
6T; 6F; 57Y; 68G |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
323768400 |
| Origin |
NTIS |
| Type |
CAT |
