Main Title |
Interlaboratory Study of Cellular Fluorescence Intensity Measurements with Fluorescein-Labeled Microbead Standards. |
Author |
Vogt, R. F. ;
Cross, G. D. ;
Phillips, D. L. ;
Henderson, L. O. ;
Hannon., W. H. ;
|
CORP Author |
NSI Technology Services Corp., Corvallis, OR. Environmental Research Lab. ;Centers for Disease Control, Atlanta, GA. |
Publisher |
c1991 |
Year Published |
1991 |
Report Number |
EPA/600/J-92/096; |
Stock Number |
PB92-153899 |
Additional Subjects |
Interlaboratory comparisons ;
Environmental monitoring ;
Data processing ;
Research and development ;
Sampling ;
Case studies ;
Quality assurance ;
Error analysis ;
Quality control ;
Statistical analysis ;
Water pollution sampling ;
Reprints ;
Watershed Manipulation Project
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB92-153899 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
13p |
Abstract |
Assessing and achieving interlaboratory comparability is a major quality assurance challenge for large interdisciplinary, multi-institutional, environmental research projects. Eight laboratories routinely measure chemical constituents of various field and laboratory derived solution samples as part of the US EPA's Watershed Manipulation Project. A quarterly interlaboratory comparison study has been designed by EPA quality assurance personnel in Corvallis, OR (USA) to assess: (1) intralaboratory precision and accuracy, (2) interlaboratory precision, and (3) trends through time. Synthetic solution samples are prepared quarterly and sent via overnight express to participating laboratories. For each analyte, laboratories are requested to perform analyses in triplicate with each replicate measured under different calibrations; precision calculated from resulting data therefore includes a component of among-batch variability. Relative bias is calculated as the percent difference between a laboratory's mean and the median of the laboratories (the supplying laboratory's value being treated equally to the other laboratories). Overall precision is expressed as the coefficient of variation using laboratory means. An ANOVA approach is also used to calculate significant differences among laboratories. Data interpretation and results from four quarterly evaluations will be presented. |
Supplementary Notes |
Pub. in Cytometry, v12 p525-536 1991. Prepared in cooperation with Centers for Disease Control, Atlanta, GA. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Interlaboratory Study of Cellular Fluorescence Intensity Measurements with Fluorescein-Labeled Microbead Standards. |
Category Codes |
68; 68D |
NTIS Prices |
PC A03/MF A01 |
Primary Description |
600/02 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
212823337 |
Origin |
NTIS |
Type |
CAT |