| Main Title |
Discriminative Stimulus Properties of Triadimefon: Comparison with Methylphenidate. |
| Author |
Perkins, A. N. ;
Eckerman, D. A. ;
MacPhail., R. C. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div. ;North Carolina Univ. at Chapel Hill. |
| Publisher |
c1991 |
| Year Published |
1991 |
| Report Number |
EPA/600/J-92/016; |
| Stock Number |
PB92-143882 |
| Additional Subjects |
Fungicides ;
Methylphenidate ;
Discrimination learning ;
Comparison ;
Rats ;
Dose-response relationships ;
Sodium chloride ;
Reprints ;
Triadimefon
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB92-143882 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
7p |
| Abstract |
Two groups of rats (N=4 each) were trained to discriminate either triadimefon (40 mg/kg) or methylphenidate (4 mg/kg) from saline in a two-lever, milk-reinforced drug discrimination paradigm. Dose response functions were determined during 5-min extinction sessions. Both agents produced a dose-related increase in the percentage of responses that occurred on the drug lever. In the substitution phase of the study, rats trained to discriminate triadimefon were tested with methylphenidate and rats trained to discriminate methylphenidate were tested with triadimefon. Triadimefon substituted completely for methylphenidate and methylphenidate substituted completely for triadimefon. The results indicate that triadimefon can function as a discriminative stimulus and that it shares discriminative stimulus properties with methylphenidate. |
| Supplementary Notes |
Pub. in Pharmacology Biochemistry and Behavior, v40 n4 p757-761 Dec 91. See also PB90-146234 and PB90-217530. Prepared in cooperation with North Carolina Univ. at Chapel Hill. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Discriminative Stimulus Properties of Triadimefon: Comparison with Methylphenidate. |
| Category Codes |
57Y; 57S; 68E |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
209921637 |
| Origin |
NTIS |
| Type |
CAT |
