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RECORD NUMBER: 1546 OF 1592

Main Title Tradescantia Micronucleus Bioassay: A Collaborative Study on Plant Genotoxicity Bioassays.
Author Ma, T. H. ; Cabrera, G. L. ; Chen, R. ; Gill, B. S. ; Sandhu, S. S. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Western Illinois Univ., Macomb. Dept. of Biological Sciences. ;Universidad Autonoma de Queretaro (Mexico). ;Charles River Analytics, Inc., Cambridge, MA. ;Ontario Ministry of the Environment, Rexdale. Biohazard Lab.
Publisher cNov 94
Year Published 1994
Report Number EPA/600/J-94/536;
Stock Number PB95-148987
Additional Subjects Bioassay ; Plants(Botany) ; Toxicity ; Toxic substances ; Pollutant identification ; Ecology ; Sodium azides ; International cooperation ; Validation ; Reliability ; Performance ; Chemical compounds ; Reprints ; Tradescantia micronucleus bioassay ; Urea/N-methyl-N-nitroso ; Glycerol/azido ; Maleic hydrazide
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NTIS  PB95-148987 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 13p
Abstract Four coded chemicals, azidoglycerol (AG), methyl nitrosourea (MNU), sodium azide (NaN3), and maleic hydrazide (MH) were tested with the Tradescantia micronucleus (Trad-MCN) bioassay by five independent laboratories from five different countries. The purpose of this international collaborative study was to evaluate four plant bioassays, of which the Trad-MCN assay was one, their sensitivity, efficiency, and reliability. The study was carried out under the auspices of the International Program on Chemical Safety, the World Health Organization, and the United Nations Environmental Program. The conclusions from this study suggest that under normal conditions, the Trad-MCN bioassay is an efficient and reliable short-term bioassay for clastogens. It is suitable for the rapid screening of chemicals, and also is specially qualified for in situ monitoring of ambient pollutants. (Copyright (c) 1994 Elsevier Science B.V.)
Supplementary Notes Pub. in Mutation Research 310, n2 p221-230 Nov 94. Prepared in cooperation with Western Illinois Univ., Macomb. Dept. of Biological Sciences., Universidad Autonoma de Queretaro (Mexico)., Charles River Analytics, Inc., Cambridge, MA., and Ontario Ministry of the Environment, Rexdale. Biohazard Lab.
Highlights Notes %AUT:A. L. /Vandenberg ;M. F. /Salamone
NTIS Title Notes Journal article.
Title Annotations Reprint: Tradescantia Micronucleus Bioassay: A Collaborative Study on Plant Genotoxicity Bioassays.
Category Codes 57C; 57Y; 57H; 68
NTIS Prices PC A03/MF A01
Primary Description 600/10
Document Type NT
Cataloging Source NTIS/MT
Control Number 503415477
Origin NTIS
Type CAT