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Main Title Letter from Chemical Manufacturers Assoc to Usepa Regarding Enclosed Materials Presented at 091086 Public Meeting with Chemical Manfacturers Assoc & Eastman Kodak Co W-attached.
CORP Author Chemical Manufacturers Association, Washington, DC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number 40-8699090
Stock Number OTS0525397
Additional Subjects Toxicology ; Health effects ; Triethylene Glycol Ethers ; Pharmaco Kinetics ; Mammals ; Humans ; In Vitro ; Subchronic Toxicity ; Rabbits ; Dermal ; Reproduction/fertility Effects ; Teratogenicity ; Rats ; Oral ; Gavage ; Toxic substances ; Laboratory animals ; CAS No 109-86-4 ; CAS No 110-80-5 ; CAS No 111-76-2 ; CAS No 111-77-3 ; CAS No 111-90-0 ; CAS No 112-34-5 ; CAS No 112-35-6 ; CAS No 112-50-5 ; CAS No 143-22-6
Library Call Number Additional Info Location Last
NTIS  OTS0525397 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 20p
Abstract Summary toxicokinetic and toxicity information regarding glycol ethers is presented. Comparitive absorption rates of glycol ethers through human epidermis in vitro ranged from 22.2 ug/sq cm/hr (for triethylene monobutyl ether) to 2705 ug/sq cm/hr (for ethylene monomethyl ether). In a dermal limit test with rabbits, each glycol ether was administered at 1 g/kg under occlusion to shaved backs of rabbits for 6 hrs/day, 5 days/week for 3 weeks. No toxic effects were noted other than irritation at the site of application. CMA briefly outlined a proposed subchronic dermal toxicity study of triethylene glycol methyl ether with rabbits.
Supplementary Notes The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
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PUB Date Free Form 2000
Category Codes 57Y; 57U; 68G; 99; 44G
NTIS Prices PC A03/MF A03
Document Type NT
Cataloging Source NTIS/MT
Control Number 028802590
Origin NTIS
Type CAT