| Main Title |
Synthesis of Haptens and Potential Radioligands and Development of Antibodies to Insect Growth Regulators Diflubenzuron and BAY SIR 8514. |
| Author |
Wie, S. I. ;
Sylwester, A. P. ;
Wing, K. D. ;
Hammock, B. D. ;
|
| CORP Author |
California Univ., Davis.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1982 |
| Report Number |
EPA-R-806447; EPA/600/J-82/468; |
| Stock Number |
PB86-230315 |
| Additional Subjects |
Chemical analysis ;
Growth regulators ;
Insects ;
Anilines ;
Nitrogen ;
Chemical reactions ;
Bromine organic compounds ;
Butyrates ;
Esters ;
Ethyl acetate ;
Metabolism ;
Antibodies ;
Reprints ;
Diflubenzuron ;
Bay Sir 8514 ;
Haptens
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-230315 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
A variety of synthetic approaches were undertaken, leading to potential haptens and radioligands for the benzoylphenylurea insect growth regulators diflubenzuron and BAY SIR 8514. One successful approach involved derivatization of the aniline nitrogen by ethyl 4-bromobutyrate followed by reaction with an appropriate isocyanate and cleavage of the ethyl ester to yield a free carboxypropyl 'handle'. Useful haptens were also synthesized by using a 3'-phenolic metabolite of diflubenzuron as well as acetate and amine functionalities in the 4' position while the N-sulfenyl bond proved too unstable for use as an antigen. |
| Supplementary Notes |
Pub. in Jnl. of Agricultural and Food Chemistry, v30 n5 p943-948 1982. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Synthesis of Haptens and Potential Radioligands and Development of Antibodies to Insect Growth Regulators Diflubenzuron and BAY SIR 8514. |
| PUB Date Free Form |
c1982 |
| Category Codes |
6F; 7D; 57P; 99A |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
628225631 |
| Origin |
NTIS |
| Type |
CAT |
