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Main Title Study of the Relationship Between Carboxyhemoglobin on Admission to the Subsequent Hospital Course of Patients Admitted to the Myocardial Infarction Research Unit at the Johns Hopkins Hospital.
Author Radford, Edward P. ; Weisfeldt., Myron L. ;
CORP Author Coordinating Research Council, Inc., New York.;Johns Hopkins Univ., Baltimore, Md. School of Hygiene and Public Health.
Year Published 1975
Stock Number PB-248 224
Additional Subjects Myocardial infarction ; Cardiovascular diseases ; Carbon monoxide ; Humans ; Patients ; Angina pectoris ; Ischemia ; Coronary artery disease ; Exposure ; Smoking ; Pathology ; Blood circulation ; Blood chemical analysis ; Carbonylhemoglobin ; Air pollution effects(Humans) ; Cigarette smoking
Library Call Number Additional Info Location Last
NTIS  PB-248 224 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 25p
Abstract On the basis of current knowledge, chronic exposure to carbon monoxide could influence the onset or severity of a myocardial infarction by two main mechanisms. (1) Animal experiments have indicated that the atheromatous process can be accelerated by sustained high carboxyhemoglobin (COHb) levels. (2) Once a coronary occlusion occurs, the severity of ischemia could be increased by the presence of carbon monoxide even in relatively low concentrations. There is very little evidence in man supporting these hypotheses. This research was undertaken to investigate patients admitted to the Johns Hopkins Hospital Emergency Ward with symptoms of chest pain, to determine if carbon monoxide at admission might relate to the severity of the infarct. The possibility that chronic exposure might play a role in the severity was also evaluated. Previously Johns Hopkins issued a final report on the studies relating carboxyhemoglobin and sudden death in Baltimore, Maryland.
Supplementary Notes Prepared in cooperation with Johns Hopkins Univ., Baltimore, Md. School of Hygiene and Public Health.
Highlights Notes Determines the relationship of exposure to carbon monoxide and severity of the infarct.
NTIS Title Notes Final rept..
PUB Date Free Form Aug 75
Category Codes 06E; 13B; 57E#; 68G#
NTIS Prices PC A02/MF A01
Document Type NT
Cataloging Source NTIS/MT
Control Number 326612820
Origin NTIS
Type CAT