Main Title |
Mycoplasma genitalium Protein Resembling the 'Mycoplasma pneumoniae' Attachment Protein. |
Author |
Hu, P. C. ;
Schaper, U. ;
Collier, A. M. ;
Clyde, W. A. ;
Horikawa., M. ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;North Carolina Univ. at Chapel Hill. ;Food and Drug Administration, Bethesda, MD. Center for Drugs and Biologics. |
Publisher |
c1987 |
Year Published |
1987 |
Report Number |
EPA/600/J-87/537; |
Stock Number |
PB91-116061 |
Additional Subjects |
Humans ;
Electron microscopy ;
Reprints ;
Bacterial proteins ;
Mycoplasma pneumoniae ;
Mycoplasma genitalium ;
Cross reactions ;
Immune sera ;
Monoclonal antibodies ;
Antigenic determinants ;
Autoradiography ;
Western blotting
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB91-116061 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
8p |
Abstract |
In previous studies with hyperimmune rabbit sera and monoclonal antibodies against P1 protein of M. pneumoniae, evidence was obtained of a shared antigenic determinant with a single protein of M. genitalium. Because of biological and morphological similarities between these two human Mycoplasma species, attempts were made to characterize this cross-reacting protein of M. genitalium (designated MgPa). The protein was surface exposed, and had an estimated molecular weight of 140 K daltons. Electron microscopy using monoclonal antibodies produced against either MgPa or P1 demonstrated that MgPa is located over the surface of the terminal structure of M. genitalium which is covered by a nap layer. These immunologic and morphologic findings suggest that the MgPa protein of M. genitalium could be the counterpart of the P1 protein of M. pneumoniae. (Copyright (c) 1987, American Society for Microbiology.) |
Supplementary Notes |
Pub. in Infection and Immunity, v55 n5 p1126-1131 May 87. Prepared in cooperation with North Carolina Univ. at Chapel Hill, and Food and Drug Administration, Bethesda, MD. Center for Drugs and Biologics. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Mycoplasma genitalium Protein Resembling the 'Mycoplasma pneumoniae' Attachment Protein. |
Category Codes |
57F; 57K; 57J |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/10 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
036522968 |
Origin |
NTIS |
Type |
CAT |