| Main Title |
Behavioral and Pharmacological Responses Following Acrylamide Exposure in Rats. |
| Author |
Rafales, L. S. ;
Bornschein, R. L. ;
Caruso, V. ;
|
| CORP Author |
Cincinnati Univ., OH. Dept. of Environmental Health.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1981 |
| Report Number |
EPA-R-805693-01-0; EPA-600/J-82-252; |
| Stock Number |
PB83-129999 |
| Additional Subjects |
Toxicology ;
Behavior ;
Exposure ;
Rats ;
Laboratory animals ;
Responses ;
Activity ;
Reprints ;
Acrylamide
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB83-129999 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
13p |
| Abstract |
The onset of acrylamide related toxicity and indications of recovery were evaluated using several behavioral tasks. Rats were chronically housed and tested for the first 15 weeks of the study in running wheels where food and water consumption and activity were continuously monitored. Separate groups of animals were repeatedly tested on at least one additional behavioral task: and operant schedule FR20 GO/NO-GO, spontaneous and drug-induced locomotor activity, drug-induced asymmetric rotation, or splaying of the hindlimbs. Animals were administered acrylamide monomer in their drinking water (100 ppm) for a six week period. Behavioral evaluations were initiated up to six weeks prior to acrylamide exposure and continued up to 12 weeks after termination of the exposure. |
| Supplementary Notes |
Pub. in Neurobehavioral Toxicology and Teratology, v4 p355-364 1982. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Behavioral and Pharmacological Responses Following Acrylamide Exposure in Rats. |
| PUB Date Free Form |
31 Jul 81 |
| Category Codes |
6T; 6O; 57Y; 57Q |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
306321673 |
| Origin |
NTIS |
| Type |
CAT |
