| Main Title |
Detection of Chemically Induced Aneuploidy in 'Saccharomyces cerevisiae': An Assessment of Mitotic and Meiotic Systems. |
| Author |
Resnick, M. A. ;
Mayer, V. W. ;
Zimmermann, F. K. ;
|
| CORP Author |
Oak Ridge National Lab., TN. ;National Inst. of Environmental Health Sciences, Research Triangle Park, NC. ;Food and Drug Administration, Washington, DC. Genetic Toxicology Branch. ;Technische Hochschule Darmstadt (Germany, F.R.). Inst. fuer Mikrobiologie.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
| Year Published |
1986 |
| Report Number |
EPA-68-02-3839; EPA/600/J-86/077; |
| Stock Number |
PB86-205572 |
| Additional Subjects |
Toxicology ;
Bacteria ;
Reprints ;
Aneuploidy ;
Mutagenesis ;
Saccharomyces cerevisiae
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-205572 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
16p |
| Abstract |
A committee of scientists was established by the U.S. Environmental Protection Agency to appraise the current state of aneuploidy test methodology, to compile and analyze published data on the chemical induction of aneuploidy, and to provide guidance for additional test development and validation. The committee was organized into 9 working groups, representing different eukaryotic organisms ranging from fungi to whole mammals. The Environmental Mutagen, Carcinogen, and Teratogen Information Program at Oak Ridge National Laboratory identified and provided literature to the working groups. The 9 reports were prepared by the individual working groups. The reports include: (1) descriptions of the available testing approaches and general principles to be followed for protocol development, (2) criteria for evaluating data, and (3) recommendations for future test development and basic research. The evaluated results are presented in tables. |
| Supplementary Notes |
Pub. in Mutation Research 167, p47-60 Jan 86. Prepared in cooperation with National Inst. of Enviromental Health Science, Research Triangle Park, NC., Food and Drug Administration, Washington, DC. Genetic Toxicology Branch, and Technische Hochschule Darmstadt (Germany, F.R.). Inst. fuer Mikrobiologie. |
| NTIS Title Notes |
Journal article (Final). |
| Title Annotations |
Reprint: Detection of Chemically Induced Aneuploidy in 'Saccharomyces cerevisiae': An Assessment of Mitotic and Meiotic Systems. |
| PUB Date Free Form |
c1986 |
| Category Codes |
6T; 57Y; 57F |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/21 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
622717274 |
| Origin |
NTIS |
| Type |
CAT |
