| Main Title |
Morphometric Characteristics of Cells in the Alveolar Region of Mammalian Lungs. |
| Author |
Crapo, J. D. ;
Young, S. L. ;
Fram, E. K. ;
Pinkerton, K. E. ;
Barry, B. E. ;
|
| CORP Author |
Duke Univ. Medical Center, Durham, NC. ;Veterans Administration Medical Center, Durham, NC.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1983 |
| Report Number |
EPA/600/J-83/279; |
| Stock Number |
PB85-176873 |
| Additional Subjects |
Cells(Biology) ;
Lungs ;
Mammals ;
Morphology ;
Characteristics ;
Humans ;
Dogs ;
Baboons ;
Rats ;
Reprints ;
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB85-176873 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
7p |
| Abstract |
Morphometric procedures have been used to study the characteristics of cells in the alveolar region of the lungs of rats, dogs, baboons, and humans. Compared with the other species, human lungs were found to contain greater numbers of macrophages and to have larger alveolar type II, endothelial, and interstitial cells. The thickness of the interstitium and the pulmonary capillary endothelium were also significantly greater in the human lungs. These differences in human lung anatomy may be due to increased exposure to airborne pollutants and to tobacco smoke. Despite the above differences and the fact that there are larger variations in size and functional characteristics of the lungs of these mammals, an overall striking similarity in characteristics of individual lung cells was found. The distribution of cells in alveolar tissue was remarkably constant between species as was the average volume and surface area of most cell types. |
| Supplementary Notes |
Prepared in cooperation with Veterans Administration Medical Center, Durham, NC. |
| Availability Notes |
Pub. in American Review of Respiratory Disease 128, n2 pS42-S46 Aug 83. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Morphometric Characteristics of Cells in the Alveolar Region of Mammalian Lungs. |
| PUB Date Free Form |
c1983 |
| Category Codes |
6E; 57O; 57F |
| NTIS Prices |
Not available NTIS |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
515818063 |
| Origin |
NTIS |
| Type |
CAT |
