||Relationship of Malathion and Its Metabolites to Fish Poisoning.
Cook, Gary H. ;
Moore, James C. ;
Coppage., David L. ;
||Environmental Research Lab., Gulf Breeze, Fla.
Toxic diseases ;
Water pollution ;
Cholinesterase inhibitors ;
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This study investigated the relation of short-term measurability of malathion and some of its metabolites in fish to poisoning of fish in the laboratory. Data indicated analysis for malathion monoacid in gut and measurement of brain acetylcholinesterase activity in fish from the natural environment are a practical measure of poisoning caused by malathion in sensitive fish. Measurable concentrations of parent compound need not be present, but acetylcholinesterase inhibition in brain must occur for fish to be poisoned.