Record Display for the EPA National Library Catalog

RECORD NUMBER: 34 OF 154

OLS Field Name OLS Field Data
Main Title Effect of imidan administered to pregnant rats /
Author Short, Robert D.
Other Authors
Author Title of a Work
Minor, Jan L.
Unger, Timothy M.
Breeden, Bradley.
Van Goethem, Dan.
Publisher U.S. Environmental Protection Agency, Health Effects Research Laboratory,
Year Published 1980
Report Number EPA 600/1-80/008; EPA-68-02-2746
Stock Number PB80-159627
OCLC Number 42930792
Subjects Insecticides--Physiological effect.
Additional Subjects Insecticides ; Toxicology ; Pesticides ; Bioassay ; Mutations ; Rats ; Laboratory animals ; Pregnancy ; Embryos ; Pathology ; Dosage ; Phosphorus organic compounds ; Teratogenesis ; Phosmet ; Fetuses ; Toxic substances
Internet Access
Description Access URL
http://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=9101FA8Y.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJAD  EPA 600/1-80-008 Region 3 Library/Philadelphia, PA 01/14/2000
EJBD ARCHIVE EPA 600-1-80-008 Headquarters Library/Washington,DC 01/30/2012
EJBD  EPA 600-1-80-008 Headquarters Library/Washington,DC 04/23/2014
EKAM  EPA 600/1-80/008 Region 4 Library/Atlanta,GA 12/03/1999
NTIS  PB80-159627 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation vi, 15 p.; 28 cm.
Abstract
The purpose of this study was to evaluate the teratogenic potential of Imidan in Wistar rats. Accordingly, groups of pregnant Wistar rats received Imidan by either a single or multiple dose protocol and their fetuses were examined for gross, soft tissue, and skeletal defects. In the single dose protocol, 30 mg/kg of Imidan was administered on gestational day 8 or 12. In the multiple dose protocol 0.06, 1.5, or 30 mg/kg of Imidan was administered every other day during gestation for a total of nine doses. No mortality which was attributed to Imidan was observed. Morbidity, as measured by reduced food consumption and weight gain was observed in dams that received 40 mg/kg of Imidan by the single and multiple dose protocol. None of the observed anomalies were increased to a statistically significant degree. Therefore, it was concluded that Imidan was not a teratogen in this study.
Notes
"EPA-600/1-80-008". EPA contract no. 68-02-2746 ; EPA project officer: Ronald L. Baron. References: p. 14.