Main Title |
Initial Submission: Dermal Sensitization of Santoflex Compounds in Humans with Cover Letter dated 08/07/1992. |
CORP Author |
Industrial and Biomedical Sensors Corp., Waltham, MA.; Monsanto Chemical Co., St. Louis, MO.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
1992 |
Report Number |
8EHQ-0892-10277 |
Stock Number |
OTS0570859 |
Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
Santoflex compounds ;
Primary dermal sensitization ;
Mammals ;
Humans ;
Dermal ;
CAS No 793-24-8 ;
CAS No 3081-01-4 ;
CAS No 3081-14-9
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS0570859 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
29p |
Abstract |
Patch tests were conducted on fifty human subjects using the Shelanski method (Proceedings of the Toilet Goods Association, No. 19, May 1953) as modified. A square of the test material was applied to the arm of each test subject and held in place with adhesive tape. After 24 hours the patch was removed and the site examined for reactions after which the material was reapplied. Reap- plications were normally made to the same site unless a 2+ or greater reaction occurred. In this event a new site was chosen. Fifteen such primary applica- tions were made except in those cases where it was deemed clinically advisable to terminate the applications earlier. Following the primary applications a two week rest was permitted after which a challenge application was applied as before. |