||Rate of Formation in vivo of the Unreactivatable Form of Brain Cholinesterase in Chickens Given DDVP or Malathion.
Witter, Robert F. ;
Gaines., Thomas B. ;
||Communicable Disease Center, Atlanta, Ga.
In vitro analysis ;
Chlorine aliphatic compounds ;
Phosphorus organic compounds ;
Laboratory animals ;
Experimental data ;
Cholinesterase inhibitors ;
Toxic substances ;
DDVP insecticide ;
Phosphoric acid/(dichlorovinyl-ester)-(dimethyl-ester) ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
The half-time for the conversion of the reversibly inhibited form of the dimethyl phosphorylated cholinesterase to the irreversibly inhibited form of this enzyme in the brains of chickens given DDVP or malathion has been found to be 2 hr. The same half-time is observed in vitro in brain homogenates inhibited with DDVP or malaoxon, the active form of malathion.