Record Display for the EPA National Library Catalog
RECORD NUMBER: 3836 OF 4452Main Title | Study of the Occurrence of Metabolites of Dimethylacetamide in the Urine of Humans and Dogs, with Cover Letter dated 09/29/1995 (Sanitized). | |||||||||||
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CORP Author | Du Pont de Nemours (E.I.) and Co., Wilmington, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. | |||||||||||
Year Published | 1995 | |||||||||||
Report Number | OTS-86960000207S | |||||||||||
Stock Number | OTS0558347 | |||||||||||
Additional Subjects | Toxicology ; Health effects ; Toxic substances ; Laboratory animals ; Pharmaco kinetics ; Mammals ; Dogs ; Dermal ; Humans ; Industrial hygiene ; CAS No 127-19-5 | |||||||||||
Holdings |
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Collation | 14p | |||||||||||
Abstract | The method developed for measuring N-methylacetamide (MMAc) in the urine consisted of concentrating the urine to small volume by evaporation, extracting the concentrated urine with redistilled dichloromethane, passing the concentrated extract through alumina to remove interfering materials and Chen measuring the anide by gas chromatography. The recovery, by this procedure, of metabolite added to urine specimens averaged 85% for seven replicate samples containing 4 ppm MHnc. The details of the method are given at the end of this report. |