Record Display for the EPA National Library Catalog

RECORD NUMBER: 120 OF 3914

OLS Field Name OLS Field Data
Main Title Acute and Chronic Toxicity Studies with Monochlorobenzene in Rainbow Trout.
Author Dalich, G. M. ; Larson, R. E. ; Gingerich, W. H. ;
CORP Author Oregon State Univ., Corvallis.;Environmental Research Lab.-Duluth, MN.
Year Published 1982
Report Number EPA-R-803090; EPA-600/J-82-397;
Stock Number PB84-116235
Additional Subjects Toxicology ; Chlorobenzenes ; Fishes ; Parenteral infusions ; Exposure ; Physiological effects ; Reprints ; Water pollution effects(Animals) ; Salmo gairdneri ; Hepatotoxicity
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB84-116235 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 19p
Abstract
The toxicity of monochlorobenzene (CB) was investigated in rainbow trout following acute intraperitoneal (i.p.) administration and chronic exposure via the water in a continuously flowing system for 15 or 30 days. In the acute study overt toxicity and hepatotoxicity was monitored over a 96-h time period. Variables measured to assess toxicity included weight changes, liver weight to body weight ratios, behavioral changes, alanine aminotransferase activity (GPT), sulfobromophthalein (BSP) retention, total plasma protein concentration and liver histopathology. In the chronic study the same measures of toxicity were followed as well as food consumption and alkaline phosphatase (AP) activity.