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RECORD NUMBER: 31 OF 35

OLS Field Name OLS Field Data
Main Title Toxicological review of chlorine dioxide and chlorite (CAS No. 10049-04-4 and 7758-19-2) : in support of summary information on the Integrated Risk Information System (IRIS) /
Author Patel, Yogendra. ; Wong, D.
Other Authors
Author Title of a Work
Wong, Diana.
CORP Author Environmental Protection Agency, Washington, DC. Office of Water.
Publisher U.S. Environmental Protection Agency, National Center for Environmental Assessment,
Year Published 2000
Report Number EPA/635/R-00/007
Stock Number PB2001-100633
Subjects Hazardous substances--Health aspects--Reporting.
Additional Subjects Toxicity ; Chlorine dioxide ; Chlorites ; Environmental exposure ; Health hazards ; Risk assessment ; Dose-response relationships ; Hazardous substances ; Carcinogens ; Chemical properties ; Physical properties ; Dermal absorption ; Carcinogenicity tests ; Toxicology ; Inhalation ; Oral dosage ; Epidemiology ; Bioassay ; Chronic disease ; Chronic exposure ; Factor analysis ; IRIS(Integrated Risk Information System)
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB2001-100633 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation 64 pages ; 28 cm
Abstract
This document presents background and justification for the hazard and dose-response assessment summaries in the U.S. Environmental Protection Agency (EPA) Integrated Risk Information System (IRIS). IRIS summaries may include an oral reference dose (RfD), inhalation reference concentration (RfC), and a carcinogenicity assessment. The RfD and RfC provide quantitative information for noncancer dose-response assessments. The RfD is based on the assumption that thresholds exist for certain toxic effects such as cellular necrosis but may not exist for other toxic effects such as some carcinogenic responses. It is expressed in units of mg/kg-day. In general, the RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the human population (including sensitive subgroups) that is likely to be without an appreciable risk of deleterious noncancer effects during a lifetime. The inhalation RfC is analogous to the oral RfD, but it provides a continuous inhalation exposure estimate. The inhalation RfC considers toxic effects for the respiratory system (portal of entry) and for effects peripheral to the respiratory system (extra respiratory or systemic effects). It is generally expressed in units of mg/m3.
Notes
"September 2000." "EPA/635/R-00/007." Includes bibliographical references. "PB2001-100633." Microfiche.