Record Display for the EPA National Library Catalog

RECORD NUMBER: 50 OF 267

OLS Field Name OLS Field Data
Main Title Chloroform Induction of Ornithine Decarboxylase Activity in Rats.
Author Savage, Jr., Russell E. ; Westrich, Carol ; Guion, Charles ; Pereira, Michael A. ;
CORP Author Health Effects Research Lab., Cincinnati, OH.
Year Published 1982
Report Number EPA-600/J-81-375;
Stock Number PB83-189050
Additional Subjects Chloroform ; Toxicology ; Carcinogens ; Malignant neoplasms ; Reprints ; Carcinogenesis ; Cancer ; Ornithine decarboxylase
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB83-189050 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 8p
Abstract
Chloroform is a drinking water contaminant that has been demonstrated to be carcinogenic to mice and rats resulting in an increased incidence of liver and kidney tumors, respectively. The mechanism of chloroform carcinogenicity might be by tumor initiation and/or promotion. Since induction of ornithine decarboxylase (ODC) activity has been proposed as a molecular marker for tumor promoters, the authors have investigated the effect of chloroform on ODC activity in rats.