Record Display for the EPA National Library Catalog
RECORD NUMBER: 21 OF 57Main Title | EPA's (Environmental Protection Agency's) Draft Drinking Water Criteria Document for Monochlorobenzene. Technical Comments of the Halogenated Organics Subcommittee. | |||||||||||
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CORP Author | Environmental Protection Agency, Washington, DC. Science Advisory Board. | |||||||||||
Year Published | 1987 | |||||||||||
Report Number | SAB/EHC-87/020; | |||||||||||
Stock Number | PB88-242706 | |||||||||||
Additional Subjects | Toxicity ; Potable water ; Biotransformation ; Carcinogens ; Liver neoplasms ; Chlorine organic compounds ; Standards ; Laboratory animals ; Exposure ; Toxic substances ; Chlorobenzene ; Health effects ; Water pollution control ; Benzene/monochloro ; Human tolerances | |||||||||||
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Collation | 10p | |||||||||||
Abstract | The Halogenated Organics Subcommittee evaluated the animal evidence for carcinogencity of chlorobenzene to be 'inadequate' under EPA's new guidelines based on the lack of a statistically significant increase in the incidence of tumors in female mice, male mice and female rats, and on the basis of the perception of a diminished biologic significance of reported malignant neoplastic nodules of the liver in the highest dose-treated male rats. The evidence would place chlorobenzene into the overall weight-of-the-evidence category D (not classified). |