Record Display for the EPA National Library Catalog
RECORD NUMBER: 439 OF 647Main Title | Papillomas on Fish Exposed to Chlorinated Wastewater Effluent. | |||||||||||
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Author | Grizzle, J. M. ; Melius, P. ; Strength, D. R. ; | |||||||||||
CORP Author | Auburn Univ., AL.;Environmental Research Lab., Gulf Breeze, FL. | |||||||||||
Year Published | 1984 | |||||||||||
Report Number | EPA/600/J-84/197; | |||||||||||
Stock Number | PB85-160844 | |||||||||||
Additional Subjects | Carcinogens ; Animal diseases ; Fishes ; Chlorination ; Water pollution ; Organic chemicals ; Mutagens ; Waste water ; Exposure ; Residues ; Reduction ; Cells(Biology) ; Electron microscopy ; Reprints ; Ictaluraus melas ; Papillomas | |||||||||||
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Collation | 12p | |||||||||||
Abstract | The presence of carcinogenic and mutagenic chemical(s) in the effluent of a wastewater treatment plant was indicated by papillomas developing on caged black bullheads (Ictaluraus melas), hepatic enzyme induction in exposed fish, and Ames test mutagenicity of organic extracts of the wastewater. Although virus-like particles have been reported in papillomas of several other fish species, no evidence was obtained for the presence of viruses in the black bullhead papillomas. Mutagenic and carcinogenic chemicals were not identified in the wastewater, but chlorination was implicated as a factor contributing to the induction of the papillomas. |