Main Title |
Mechanisms of carcinogenesis in risk identification |
Other Authors |
|
Publisher |
International Agency for Research on Cancer ; |
Year Published |
1992 |
OCLC Number |
29225008 |
ISBN |
9283221168 |
Subjects |
Carcinogenesis ;
Carcinogenicity testing ;
Carcinogenicity Tests ;
Carcinogens ;
Neoplasms--etiology ;
Neoplasms--genetics
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EKBD |
IARC/SP-116 |
|
Research Triangle Park Library/RTP, NC |
09/01/1995 |
|
Collation |
xiv, 615 p. : ill. ; 25 cm. |
Notes |
Includes bibliographical references and indexes. |
Contents Notes |
Critical molecular targets in chemical carcinogenesis -- Genes and gene products that regulate proliferation and differentiation: critical targets in carcinogenesis / J.L. Bos and C.F. van Kreijl -- Tumour suppressor genes, multistage carcinogenesis and molecular epidemiology / C.C. Harris -- Receptor-mediated carcinogenesis / G.W. Lucier -- Mechanisms of carcinogenicity -- Mechanisms of action of known human carcinogens / J.C. Barrett -- Use of short-term tests in determining the genotoxicity or nongenotoxicity of chemicals / J. Ashby -- Performance of tests for cell transformation and gap-junction intercellular communication for detecting nongenotoxic carcinogenic activity / S.H.H. Swierenga and H. Yamasaki -- Genotoxic and nongenotoxic carcinogens: mechanisms of action and testing strategies / C. Ramel -- Use of 32P-postlabelling to distinguish between genotoxic and nongenotoxic carcinogens / D.H. Phillips -- Peroxisome proliferation and hepatocarcinogenesis / J.K. Reddy and M.S. Rao -- Immunosuppression and cancer / L.J. Kinlen. (cont) Sex hormones and cancer / T.J.A. Key and V. Beral -- Structure-activity relationships for carcinogens with different modes of action / H.S. Rosenkranz -- Chemically induced cell proliferation in carcinogenesis / B.E. Butterworth ... {et al.} -- Role of DNA repair in carcinogenesis / B.W. Stewart -- Animal carcinogenicity tests and their interpretation -- Chemicals classified by IARC: their potency in tests for carcinogenicity in rodents and their genotoxicity and acute toxicity / D.B. McGregor -- Medium-term bioassays for carcinogens / N. Ito, T. Shirai and R. Hasegawa -- Predictive value of hepatic preneoplastic lesions as indicators of carcinogenic response / P. Bannasch and H. Zerban -- Transgenic mice in carcinogenicity testing / R. Griesemer and R. Tennant -- Chemical toxicity and chemical carcinogenesis. Is there a causal connection? A comparative morphological evaluation of 1500 experiments / J.E. Huff -- Species-specific
mechanisms of carcinogenesis / J.A. Swenberg ... {et al.}. (cont) Species differences in carcinogen metabolism and interspecies extrapolation / E. Dybing and H.S. Huitfeldt -- Biological markers in exposed humans -- Significance of DNA and protein adducts / K. Hemminki -- Biological markers in exposed humans: gene mutation / B. Lambert -- Human cytogenetic damage as a predictor of cancer risk / M. Sorsa, J. Wilbourn and H. Vainio -- Data analysis and modelling -- Considerations in the conduct of meta-analysis using data from animal carcinogenicity experiments / B. McKnight -- Meta-analysis of epidemiological studies of carcinogenesis / J. Peto -- Dose-response relationships in carcinogenesis / D. Krewski, M.J. Goddard and J.M. Zielinski -- Role of epidemiological observation in elucidating the mechanisms of carcinogenesis / J. Kaldor.
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