Record Display for the EPA National Library Catalog
RECORD NUMBER: 309 OF 313
|OLS Field Name||OLS Field Data|
|Main Title||Use of genotoxic activity profiles in assessment of carcinoensis and genetic effects /|
|Author||Waters, Michael D. ; Stack, H. F. ; Brady, A. L.|
|CORP Author||Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC.|
|Publisher||U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory,|
|Additional Subjects||Toxicity ; Mutagens ; Carcinogens ; Hazardous materials ; Bioassay ; Dosage ; Organic compounds ; Computer programs ; Mutagenicity tests ; Carcinogenicity tests ; Risk assessment|
|Collation||23 pages ; 28 cm|
A methodology has been developed to display and evaluate multiple test quantitative information on genetic toxicants for purposes of assessing carcinogenesis and transmissible genetic effects. Genetic activity profiles were prepared which illustrate a quantitative data base on the genetic and related effects of nearly 200 chemicals for which some data are available on carcinogenicity in humans. This information may be used for purposes of comparative chemical hazard assessment. Together with information derived from animal cancer tests and human epidemiological studies, assessments may be made regarding potential human health risks associated with exposure to chemical substances.
EPA/600/D-89/087. PB89-222830. Microfiche.