Main Title |
Evaluation of In Vitro Production of the Beta Chemokine, MCP-1, as a Diagnostic Test in diisocyante Asthma, with Cover Letter dated 03/03/1999. |
CORP Author |
International Isocyanate Inst., Parsippany, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
1999 |
Stock Number |
OTS0573880 |
Additional Subjects |
Toxicology ;
Health effects ;
Benzene ;
1 ;
3-Diisocyanatomethyl ;
Biochemistry ;
Mammals ;
Humans ;
In vitro ;
Industrial hygiene ;
CAS No 26471-62-5
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS0573880 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
14p |
Abstract |
The primary aim of this proposal is to validate dlisocyanate (DIISO) specific in vitro cellular MCP-1 as a diagnostic marker of occupational asthma (OA) by using the specific bronchoprovocation test (SBPT) as the gold standard for diagnosis. A secondary aim of the study is to evaluate the sensitivity and specificity ofin vitro serum DIISO-HSA specific IgG and IgE responses for identification ofdiisocyanate asthma (DA) confirmed by the SBPT. This report summarizes and discusses the results obtained in this study. |