Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Histopathology.
Author Meyers, T. R. ; Hendricks, J. D. ;
CORP Author Oregon State Univ., Corvallis. Agricultural Experiment Station.;Environmental Research Lab., Gulf Breeze, FL.
Year Published 1985
Report Number TP-5591; EPA/600/D-85/034;
Stock Number PB85-167955
Additional Subjects Toxicology ; Chemical compounds ; Aquatic animals ; Pathology ; Toxicity ; Death ; Cause effect relationships ; Physiology ; Biochemistry ; Water pollution effects(Animals) ; Histopathology
Library Call Number Additional Info Location Last
NTIS  PB85-167955 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 53p
Overt signs of toxicity (loss of appetite, loss of equilibrium, discoloration, or death) are nearly always preceded by biochemical, physiological, and/or morphological changes in the organism. The ability to qualitatively or quantitatively measure these changes prior to death of the organism can often provide early indications of toxicity and valuable insights into the mechanisms of toxicity. This chapter concerns the field of histopathology and its importance, use, and application in aquatic toxicology. Histopathology is the study of the structure of abnormal tissue. Examination of tissues from fish and other aquatic organisms after death may serve to identify the cause of death and possibly the causative agent. This information along with physiological and biochemical data may provide a more complete and accurate description of the activity of a chemical agent.