Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Cell Cycle Regulation [electronic resource] /
Author Kaldis, Philipp.
Publisher Springer Berlin Heidelberg,
Year Published 2006
Call Number QH573-671
ISBN 9783540345534
Subjects Life sciences. ; Oncology. ; Biochemistry. ; Cytology.
Internet Access
Description Access URL
Collation XII, 374 p. 26 illus., 1 in color. online resource.
Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes
The cell cycle is tightly regulated on many different levels to ensure properly controlled proliferation. Deregulation of cell cycle regulation is a hallmark of cancer. In this book, many aspects of cell cycle regulation are discussed, which include G1, S, M phase control, ubiquitin-mediated degradation, DNA damage response, mitotic spindle checkpoint, the centrosome cycle, Retinoblastoma protein family, the Myc oncogene, and mouse models for tumor suppressors, cyclin-dependent kinases, and meiosis. These chapters written by experts provide an updated view on how the cell cycle is regulated in vivo and about the involvement of cell cycle regulators in cancer.