Main Title |
Development and Assessment of Procedures for Collection, Chemical Characterization and Mutagenicity Testing of Ambient Air. |
Author |
Kolber, A. R. ;
Hughes, T. J. ;
Wolff, T. J. ;
Little, L. W. ;
Sparacino, C. M. ;
|
CORP Author |
Research Triangle Inst., Research Triangle Park, NC. ;Little (L. W.) Associates, Raleigh, NC.;Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1983 |
Report Number |
EPA-68-02-2724; EPA-600/2-83-045; |
Stock Number |
PB83-220046 |
Additional Subjects |
Gas analysis ;
Toxicity ;
Organic compounds ;
Bioassay ;
Assessments ;
Chemical analysis ;
Carcinogens ;
Particles ;
Air pollution ;
Distillation ;
Solvent extraction ;
Sampling ;
Toxicity ;
Mutagens ;
Industrial wastes ;
Exhaust emissions ;
Potable water ;
Air pollution detection ;
Air water interfaces ;
Procedures
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB83-220046 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
241p |
Abstract |
The overall objective of this Research Triangle Institute pilot study was to develop and evaluate a minimal testing protocol which could detect and quantify the mutagenic potential of ambient air. The cost-effective biological and chemical testing protocol developed under this program outlines sampling, chemical fractionation/identification, and bioassay techniques which are applicable to air pollution testing of both ambient air particles and vapors. More specifically, this study: (1) evaluated the three stage Massive Air Volume Sampler (MAVS), developed by Battelle for collection of air particle samples; (2) developed and utilized a chemical fractionation scheme for solvent extraction of organic compounds from ambient air particles; (3) evaluated a GC/MS/Computer analysis system designed to chemically identify signature mutagens/carcinogens; and (4) utilized and evaluated modifications of the Ames/Salmonella typhimurium mutagenicity assay for ambient air particles and vapors. |