Record Display for the EPA National Library Catalog
RECORD NUMBER: 4 OF 82
|OLS Field Name||OLS Field Data|
|Main Title||Acrylamide and Methacrylamide-Subchronic Percutaneous Toxicity Study in New-Born Rabbets. Prepared by Dublin Labs. with Cover Letter.|
|CORP Author||Rohm and Haas Co., Philadelphia, PA.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.|
|Publisher||14 Nov 1975|
|Additional Subjects||Toxicity ; Percutaneous ; Laboratory animals ; Rabbits ; Neurotoxicity ; Neurotoxic effects ; Hematology ; Serum biochemical analyses ; Acrylamide ; Methacrylamide|
Daily doses of methacrylamide were administered percutaneously to separate groups of newborn rabbits; controls received vehicle. At 5 weeks, one-half of the rabbits in each group were killed. The remaining rabbits, which received the highest dose of each compound, were removed from treatment and observed for 7 weeks. Those rabbits receiving the lower doses were continued on treatment. All of the animals were killed at 12 weeks.