Main Title |
Prediction of the Solubility of Hydrophobic Compounds in Nonideal Solvent Mixtures. |
Author |
Pinal, R. ;
Lee, L. S. ;
Rao., P. S. C. ;
|
CORP Author |
ROCOM, Montclair, NJ. ;Florida Univ., Gainesville. Dept. of Soil Science.;Robert S. Kerr Environmental Research Lab., Ada, OK. |
Publisher |
c1991 |
Year Published |
1991 |
Report Number |
EPA-R-814512; EPA/600/J-92/027; |
Stock Number |
PB92-143999 |
Additional Subjects |
Aromatic polycyclic hydrocarbons ;
Solubility ;
Organic solvents ;
Mixtures ;
Sorption ;
Gibbs free energy ;
Mathematical models ;
Reprints ;
Hydrophobic organic chemicals ;
Nonideal solvent mixtures ;
Cosolvency
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB92-143999 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
15p |
Abstract |
The solubility of hydrophobic organic chemicals (HOCs) in partially-miscible solvent mixtures was investigated. In agreement with previous findings, it was observed that there is a limited domain in which nonideality effects are important; appreciable concentrations of partially-miscible (with water) organic solvents are required in order to observe significant effects on solubility. Deviations from the log-linear cosolvency model were attributed to solvent-solvent interactions, and hence quantified by the degree of nonideality of the solvent mixture. An expression was proposed for estimating the deviations from the log-linear model. For each solvent component, a nonideality term closely related to its partial excess free energy of mixing was added to the log-linear model. Predictions of solubility in binary and ternary solvent mixtures were in good agreement with experimental data. Deviations from the log-linear model were attributed to solvent nonideality which implies that there is no fundamental or mechanistic difference between the cosolvencies of partially- and completely- miscible solvents. The observed differences in cosolvencies are only in magnitude, which results from a combination of the degree of nonideality of the mixture (activity coefficients) and concentrations of the components. Examples of the application of the proposed expression are presented. |