Main Title |
Health assessment document for acrolein / |
Author |
Chiu, Arthur. ;
Clegg, E. ;
Davidson, I. ;
Dippel, C. ;
Kaufman, L.
|
CORP Author |
United States. Environmental Protection Agency. Environmental Criteria and Assessment Office. |
Publisher |
Environmental Criteria and Assessment Office, Office of Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, |
Year Published |
1986 |
Report Number |
EPA/600/8-86/014A |
Stock Number |
PB87-139960 |
OCLC Number |
14920191 |
Subjects |
Toxins ;
Acroleins--Toxicology
|
Additional Subjects |
Toxins ;
Acrolein--Toxicology ;
Carcinogens ;
Exposure ;
Assessments ;
Hazardous materials ;
Concentration(Composition) ;
Epidemiology ;
Laboratory animals ;
Toxic substances ;
Carcinogenesis ;
Chromosomal aberrations
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EHAM |
EPA/600/8-86/014A |
|
Region 1 Library/Boston,MA |
05/25/2016 |
EJBD |
EPA 600-8-86-014A |
|
Headquarters Library/Washington,DC |
08/19/2016 |
EJED |
EPA 600/8-86-014A |
|
OCSPP Chemical Library/Washington,DC |
01/01/1988 |
EKBD |
EPA-600/8-86-014A |
|
Research Triangle Park Library/RTP, NC |
04/23/2004 |
ELBD ARCHIVE |
EPA 600-8-86-014A |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
DISPERSAL |
ERAD |
EPA 600/8-86-014A |
|
Region 9 Library/San Francisco,CA |
02/20/2013 |
ESAD |
EPA 600-8-86-014A |
|
Region 10 Library/Seattle,WA |
03/23/2010 |
NTIS |
PB87-139960 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
1 volume (various pagings) : illustrations ; 28 cm |
Abstract |
Acrolein is an unsaturated aldehyde which is highly toxic by the inhalation and oral routes and is a strong irritant. The reactivity and toxicity of acrolein is seen at the principal sites of exposure, the gastrointestinal and pulmonary tracts. There is no evidence that below aversive levels, acrolein enters the general circulation. Acrolein is metabolized by liver and lung; metabolism is the principal route of elimination. There is inadequate evidence for acrolein's mutagenicity or chemical interaction with mammaliam germ cells. Animal evidence for carcinogenicity is limited. There is no epidemiological data. Acrolein can produce both embryotoxic and fetotoxic effects, and it is teratogenic under certain conditions. |
Notes |
Includes bibliographical references. "September 1986." "External review draft." "EPA/600/8-86/014A." |