Main Title |
Toxicokinetic Modeling of (14)C-Pentachlorophenol in the Rainbow Trout ('Salmo gairdneri). |
Author |
McKim, J. M. ;
Schmieder, P. K. ;
Erickson, R. J. ;
|
CORP Author |
Environmental Research Lab.-Duluth, MN. |
Year Published |
1986 |
Report Number |
EPA/600/J-86/295; |
Stock Number |
PB87-176434 |
Additional Subjects |
Fishes ;
Toxicology ;
Absorption ;
Metabolism ;
Elimination ;
Dosimetry ;
Reaction kinetics ;
Reprints ;
Pentachlorophenol ;
Water pollution effects(Animals) ;
Bioconcentration ;
Xenobiotics ;
Risk assessment
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB87-176434 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
24p |
Abstract |
An in vivo trout model was used to monito the major routes and rates of pentachlorophenol uptake and elimination. A first-order kinetic model and observed data were used to generate fitted and predicted rate constants required for evaluation of first-order kinetic. The fitted first-order uptake-depuration curves for all experimental animals agreed with those observed suggesting first-order kinetics approximated the behavior of whole-body (14)C-pentachlorophenol (PCP) burden. |