Record Display for the EPA National Library Catalog


Main Title Lack of Effects of Carbon Monoxide on Human Vigilance.
Author Benignus, Vernon A. ; Otto, David A. ; Prah, James D. ; Benignus., Gayla ;
CORP Author Health Effects Research Lab., Research Triangle Park, N.C. Clinical Studies Div.
Year Published 1977
Report Number EPA/600/J-77/100;
Stock Number PB-278 632
Additional Subjects Toxicity ; Carbon monoxide ; Vigilance ; Humans ; Reviews ; Males ; Monitors ; Concentration(Composition) ; Exposure ; Respiration ; Behavior ; Experimental data ; Physiological effects ; Blood chemical analysis ; Toxic substances ; Reprints ; Carbonylhemoglobin ; Air pollution effects(Humans) ; Behavior toxicology
Library Call Number Additional Info Location Last
NTIS  PB-278 632 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
Previous publications on the effects of low levels of carbon monoxide (CO) on human vigilance performance have found conflicting results. While several studies have found statistically reliable effects, none have gone unchallenged. This article presents a critical review of the literature and the results of a study employing 52 human male subjects performing a numeric monitoring task. CO levels were 0, 100, 200 ppm which produced mean carboxyhemoglobin levels of 0.01, 4,61 and 12.62 percent respectively. No CO exposure levels produced any effect on vigilance performance. The power of the statistical test for CO effects was shown to be quite high, even for fairly trivial possible decrements of performance.