Record Display for the EPA National Library Catalog


Main Title Evaluation of the Dermal Carcinogenic Potential of Pentaerythritol Acrylate-HF with Attachments and Cover Letter dated 07/28/88.
CORP Author Union Carbide Corp., Danbury, CT. ;Carnegie-Mellon Inst. of Research, Pittsburgh, PA.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 2 Aug 1988
Year Published 1988
Report Number FYI-OTS-0888-0629;
Stock Number OTS-0000629
Additional Subjects Carcinogens ; Dermal absorption ; Toxicity ; Chemical hygine ; Malignant neoplasms ; Tumors ; Pentaerythritol aerylate-HF ; Union Carbide Corporation(Trademark) ; 511-01-6656 ; 16-CHC-111-3
Library Call Number Additional Info Location Last
NTIS  OTS-0000629 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 18p
Forty C3H/HeJ male mice were painted 3 times per week for their lifespan on the skin of the back, clipped free of fur, with pentaerythritol acrylate-HF as a 15% dilution in acetone at an average dose of 0.0026 grass pentaerythritol acrylate-HF/mouse/application. A negative control group of 40 C3H/HeJ male mice received repeated skin paintings of undiluted acetone at an average dose of 0.012 grams/mouse/application. No skin tumors were observed in the group of mice painted with pentaerythritol acrylate-HF. One mouse in the group painted with acetone had a histologically verified squamous cell carcinoma of the skin near the right eye which may or may not have been due to treatment.