Record Display for the EPA National Library Catalog


Main Title Tier I Microbial Mutagenesis Studies for Four E.I. Dupont de Nemours and Company Chemicals with Cover Letter.
CORP Author Du Pont de Nemours (E.I.) and Co., Wilmington, DE. DuPont Environmental Remediation Services.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 27 Jun 1983
Year Published 1983
Report Number OTS-878213773;
Stock Number OTS-0206335
Additional Subjects Microbial processes ; Mutagenic pathways ; Microbiology ; Salmonella ; Strains ; In vitro analysis ; Toxicity ; Rats ; Chemical analysis ; Metabolism ; Phenylene radicals ; Saccharomyces ; Phenobarbitol ; Liver ; EI DuPont De Nemours and Company ; P-Phenylenediamine ; Typhimurium
Library Call Number Additional Info Location Last
NTIS  OTS-0206335 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 51p
SRI conducted in vitro microbiological mutagenicity experiments on four chemicals for E.I. du Pont de Nemours & Co. The chemicals were identified to us as 9008, 9221, 9222, and 9223. Assays were conducted with four strains of Salmonella (TA1535, TA1537, TA1538, and TA100) and with Saccharomyces cerevisiae DS. All assays were conducted in the presence and in the absence of a phenobarbitol-stimulated rat-liver homogenate metabolic activation system. Three of the chemicals, 9008, 9221, and 9222, were mutagenic in assays with S. typhimurium TA1538 but were not mutagenic with the other S. Typhimurium strains. None of the chemicals were mutagenic in the S. cerevisiae D3 assays.