Record Display for the EPA National Library Catalog


Main Title Asbestos and gastro-intestinal cancer : cell culture studies /
Author Reiss, B., ; Weisburger, J. H. ; Williams, G. M.
Other Authors
Author Title of a Work
Weisburger, J. H.,
Williams, G. M.
CORP Author American Health Foundation, Valhalla, NY. Naylor Dana Inst. for Disease Prevention.;Health Effects Research Lab., Cincinnati, OH.
Publisher Environmental Protection Agency, Office of Research and Development [Office of Health and Ecological Effects], Health Effects Research Laboratory, For sale by the National Technical Information Service.
Year Published 1979
Report Number EPA-600/1-79-023; EPA-R-803998-01; PB300474
Stock Number PB-300 474
OCLC Number 05511211
ISBN pbk.
Subjects Asbestos--Toxicology ; Cell culture ; Intestines--Cancer ; Stomach--Cancer ; Asbestos--toxicity ; Cell Culture Techniques ; Intestinal Neoplasms--etiology ; Stomach Neoplasms--etiology
Additional Subjects Asbestos ; Malignant neoplasms ; Gastrointestinal system ; Toxicology ; Silicate minerals ; Humans ; Intestines ; Liver ; Rats ; Concentration(Cimposition) ; Recommendations ; Exposure ; Air pollution ; In vitro analysis ; Embryos ; Mice ; Cancer ; Cell cltures ; Cytotoxicity ; Mutagenesis ; Toxic substances ; Environmental health ; Air polluion effects(Humans) ; Biological effects
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA 600-1-79-023 Headquarters Library/Washington,DC 04/28/2014
EJBD  EPA 600-1-79-023 c.1 Headquarters Library/Washington,DC 05/21/2014
EKBD  EPA-600/1-79-023 Research Triangle Park Library/RTP, NC 09/07/2001
NTIS  PB-300 474 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation viii, 37 pages : illustrations ; 28 cm
Three forms of asbestos: amosite, crocidolite, and chrysotile, were assayed for their cytotoxicity and mutagenicity in cell clture. Using embjryonic human intestine derived and adult rat liver derived epitelial cells, the order of toxicity was chrysotile > amosite = crocidolite. Leaching in acid slightly increased the toxicity of amosite and crocidolite and greatly decreased the toxicity of chrysotile. High concentrations of all three asbestos forms were not mutagenic in cultures of rat liver-derived epithelial cells.
Grant no. R-803998-01. "EPA-600/1-79-023." July 1979. Includes bibliographical references (pages 32-36).