1. Cascading trophic interactions / J.F. Kitchell and S.R. Carpenter -- 2. Experimental lakes, manipulations and measurements / S.R. Carpenter and J.F. Kitchell -- 3. Statistical analysis of the ecosystem experiments / S.R. Carpenter -- 4. The fish populations / J.R. Hodgson, X. He, and J.F. Kitchell -- 5. Fish behavioral and community responses to manipulation / X. He, R. Wright and J.F. Kitchell -- 6. Roles of fish predation: piscivory and planktivory / X. He, J.F. Kitchell, J.R. Hodgson, R. Wright, P.A. Soranno, D.M. Lodge, P.A. Cochran, D. Benkowski and N. Bouwes -- 7. Dynamics of the phantom midge: implications for zooplankton / P.A. Soranno, S.R. Carpenter and S.M. Moegenburg -- 8. Zooplankton community dynamics / P.A. Soranno, S.R. Carpenter and M.M. Elser -- 9. Effects of predators and food supply on diel vertical migration of Daphnia / M.L. Dini, P.A. Soranno, M.D. Scheuerell and S.R. Carpenter -- 10. Zooplankton biomass and body size / P.A. Soranno, S.R. Carpenter and X. He -- 11. Phytoplankton community dynamics / S.R. Carpenter, J.A. Morrice, J.J. Elser, A.L. At. Amand and N.A. MacKay -- 12. Metalimnetic phytoplankton dynamics / A.L. St. Amand and S.R. Carpenter -- 13. Primary production and its interactions with nutrients and light transmission / S.R. Carpenter, J.A. Morrice, P.A. Soranno, J.J. Elser, N.A. MacKay and A.L. St. Amand -- 14. Heterotropic microbial processes / M.L. Pace -- 15. Annual fossil records of food-web manipulation / P.R. Leavitt, P.R. Sanford, S.R. Carpenter, J.F. Kitchell and D. Benkowski -- 16. Simulation models of the trophic cascade: predictions and evaluations / S.R. Carpenter and J.F. Kitchell -- 17. Synthesis and new directions / J.F. Kitchell and S.R. Carpenter. Fluctuations in top predator populations in lakes can cascade through food webs to alter nutrient cycling, algal biomass and primary production. Trophic cascades may interact with nutrients and physical factors to explain most of the variance in lake ecosystem process rates. In this book, a multidisciplinary research team tests this idea by manipulating whole lakes experimentally, and coordinating this with paleolimnological studies, simulation modeling, and small-scale enclosure experiments. Consequences of predator-prey interactions, behavioral responses of fishes, diel vertical migration of zooplankton, plankton community change, primary production, nutrient cycling and microbial processes are described. Paleolimnological techniques enable the reconstruction of trophic interactions from past decades. Prospects for analysing the interaction of food web structure and nutrient input in lakes are explored. This book will be of interest to graduate students and researchers in the fields of ecology, aquatic ecology, resource management and limnology.