The following report describes a project that continued to develop and populate a bibliographic database in support of the National Children's Study. The purpose of this work assignment was to identify recently published literature that may be relevant to biomarkers and children's health and to add the literature citations to the existing database. Another purpose was to make enhancements to the search capabilities of the database and to update the User's Guide. The database contains literature on biomarkers of exposure, susceptibility, or effect, and an associated health outcome. Literature identified during the search was captured in an electronic database and reviewed for relevance. The final database, called the Biomarkers Database, is a searchable reference tool that scientific investigators may use for future research efforts. The work assignment included a literature search, abstract screening process, revision of a preexisting database, search enhancements to the database, and revision of a User's Guide. We reviewed the search strategy and revised several of the search terms using the terms provided in the Final Report and User's Guide from August 25, 2003. We protected the integrity of the pre-existing data in the Biomarkers Database and only added new records. Previously, the Biomarkers Database contained 4,336 records; after our literature search, the database contains 5,889 records. In addition, new search features were added to the database, providing the ability to search on multiple terms in the majority of the fields. The User's Guide was also added into the database.