Record Display for the EPA National Library Catalog


Main Title Content of platinum and palladium in rat tissues : correlation of tissue concentrations of platinum and palladium with biochemical effects /
Author Holbrook, David J., ; Holbrook, David J., Jr.
CORP Author North Carolina Univ. at Chapel Hill. Dept. of Biochemistry.;Health Effects Research Lab., Research Triangle Park, N.C.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory,
Year Published 1977
Report Number EPA 600/1-77/051; EPA-Z804557-01; PB275522
Stock Number PB-275 522
OCLC Number 40998114
Subjects Platinum--Physiological effect. ; Palladium--Physiological effect.
Additional Subjects Platinum ; Palladium ; Toxicology ; Air pollution ; Motor vehicles ; Exhaust emissions ; Diets ; Ingestion(Biology) ; Tissues(Biology) ; Deposition ; Metabolism ; Drugs ; Biochemistry ; Body weight ; Dose rate ; Rats ; Laboratory animals ; Bioassay ; Proteins ; Metals ; Chemical bonds ; Environmental health ; Catalytic converters ; Air pollution control equipment ; Air pollution effects(Animals)
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA 600-1-77-051 Headquarters Library/Washington,DC 06/04/2012
EJBD  EPA 600-1-77-051 Headquarters Library/Washington,DC 05/16/2014
EKBD  EPA-600/1-77-051 Research Triangle Park Library/RTP, NC 06/06/2003
ELBD  EPA 600-1-77-051 AWBERC Library/Cincinnati,OH 09/02/2016
NTIS  PB-275 522 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation vi, 14 pages ; 28 cm.
Platinum and palladium are used as the active components in the catalytic converters of air pollution control devices of motor vehicles. The use of these metals is accompanied by the potential loss of platinum and palladium into the environment. This laboratory has been involved in studies on the biochemical effects of these metals. Data have been compiled on the platinum and palladium content in six rat tissues after the dietary administration of platinum or palladium salts. The platinum and palladium content in rat tissues does not appear to correlate with the rates of weight gain of rats, the organ weights, or the four parameters of drug metabolism which were studied.
"EPA-600/1-77-051." EPA contract no. Z804557-01; EPA project officer: M.F. Copeland. Includes bibliographical references (page 13).