||Organic Phosphorus Poisoning and Its Therapy, with Special Reference to Modes of Action and Compounds that Reactivate Inhibited Cholinesterase.
Durham, William F. ;
Hayes, Jr., Wayland J. ;
||Environmental Protection Agency, Wenatchee, Wash. Field Studies Section.
Phosphorus organic compounds ;
Toxic diseases ;
Sign and symptoms ;
Cholinesterase inhibitors ;
Laboratory animals ;
Nitrogen organic compounds ;
Pyridinium/((hydroxy imino)methyl)-methyl-iodide ;
||Some EPA libraries have a fiche copy filed under the call number shown.
;Contents: Nature and physiologic function of cholinesterase; Symptoms of organic phosphorus poisoning; Mechanism of inhibition of cholinesterase; Measurement of cholinesterase activity and its relationship to symptomatology; Measurement of metabolites and their relationship to symptomatology; Use and action of atropine and other nonspecific antidotes; Development of specific antidotes; Chemica ans physiologic properties of oximes; Antidotal efficacy of oximes in poisoned experimental animals; Application of 2-PAM in poisoining in man; Suggestions for treatment; Prevention of poisoning.