Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Separation Characteristics of Alkylated Guanines in High-Performance Liquid Chromatography.
Author Xue, W. ; Carlson, R. M. ;
CORP Author Minnesota Univ.-Duluth. Dept. of Chemistry.;Environmental Research Lab.-Duluth, MN.
Publisher c1988
Year Published 1988
Report Number EPA-R-813144 ;EPA-R-813943; EPA/600/J-88/457;
Stock Number PB90-147646
Additional Subjects Separation ; Guanines ; Chemical analysis ; Chromatographic analysis ; Deoxyribonucleic acids ; Carcinogens ; Mutagens ; In vitro analysis ; In vivo analysis ; Isomerization ; pH ; Capacity ; Reprints ; High performance liquid chromatography ; Retention functions
Library Call Number Additional Info Location Last
NTIS  PB90-147646 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/15/1990
Collation 13p
The retention behavior of thirteen alkylated guanines on normal-phase silica gel and amino columns and on reversed-phase ODS and phenyl columns was studied. The larger the alkyl substituent at the same position of guanine the weaker was the retention in the normal-phase chromatographic system and the greater the retention during reversed-phase chromatography. O(6)Derivatives possess the lowest polarity in each set of isomers. An amino column was found to be of highest efficiency in terms of separation of the set of ethylguanine isomers and of benzylguanines studied. A phenyl column provided the best resolution of methylated guanines. (Copyright (c) 1988 Elsevier Science Publishers R.V.)