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Main Title Investigation of selected potential environmental contaminants : halogenated benzenes /
Author Ware, Sylvia A. ; West., William L.
Other Authors
Author Title of a Work
West, William L.
CORP Author Ebon Research Systems, Washington, D.C.;Environmental Protection Agency, Washington, D.C. Office of Toxic Substances.
Publisher U.S. Environmental Protection Agency, Officeof Toxic Substances,
Year Published 1977
Report Number EPA-560/2-77-004; EPA-68-01-4183
Stock Number PB-273 206
OCLC Number 31716565
Subjects Benzene--Environmental aspects ; Benzene--Toxicology
Additional Subjects Halogen organic compounds ; Reviews ; Environmental surveys ; Soil analysis ; Bromine organic compounds ; Iodine organic compounds ; Chlorine organic compounds ; Fluorine organic compounds ; Air pollution ; Potable water ; Concentration(Composition) ; Cargo transport ; Storage ; Industrial wastes ; Public health ; Toxicology ; Physical properties ; Chemical properties ; Marketing ; Chemical industry ; Chemical analysis ; Air pollution ; Surface water ; Utilization ; Regulations ; Standards ; Manufacturing ; Monitoring ; Costs ; Benzenes ; Liquid wastes ; Bioaccumulation
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD  EPA 560-2-77-004 Headquarters Library/Washington,DC 09/09/2015
EKBD  EPA-560/2-77-004 Research Triangle Park Library/RTP, NC 07/23/2012
ELBD ARCHIVE EPA 560-2-77-004 Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023 DISPERSAL
EMBD  EPA/560/2-77/004 NRMRL/GWERD Library/Ada,OK 12/08/1995
ESAD  EPA 560-2-77-004 Region 10 Library/Seattle,WA 03/23/2010
NTIS  PB-273 206 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation xi, 283 pages : illustrations ; 28 cm
This report reviews the potential environmental hazard from use of the halogenated benzenes. Major focus is in the commercially important chlorinated benzenes, though fluorinated, brominated and iodinated benzenes are also discussed as well as mixed halogen compounds. Hexachlorobenzene is not included in this study except where information relates to trends within the group of chlorinated benzenes. Chlorinated benzenes are used as solvents, chemical intermediates, for moth repellency and as space odorizers. Several chlorinated benzenes have been detected in drinking and raw water sources throughout the U.S. p-Dichlorobenzene has been found in human blood samples from New Orleans, and with 1, 2, 4, 5-tetrachlorobenzene and hexachlorobenzene in human adipose tissue samples collected in Tokyo, Japan. While of comparatively low acute toxicity, chronic or 'subacute' effects are seen at fairly low concentrations. These effects include: porphyria, necrosis of liver, kidneys and lungs, and possible blood abnormalities. Several of the chlorinated benzenes are known mutagens in plants. Carcinogenic studies completed were of a short duration and must be considered inconclusive until studies are repeated using current methodologies. The extent of metabolism of these compounds depends on the degree of substitution, the position(s) of substitution and the type of halogen.
"July 1977." "Project Officer: Frank J. Letkiewicz." Final report. "EPA-560/2-77-004." Includes bibliographical references (pages 261-283).