Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Sensitivity, Specificity and Accuracy of the Arabidopsis Assay in the Identification of Carcinogens.
Author Redei, G. P. ; Acedo, G. N. ; Andhu, S. S. ;
CORP Author Missouri Univ.-Columbia.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1984
Report Number EPA-R-807892; EPA-600/D-84-105;
Stock Number PB84-182195
Additional Subjects Carcinogens ; Bioassay ; Bacteria ; In vitro analysis ; In vivo analysis ; Sensitivity ; Mutagens ; Identifying ; Accuracy ; Arabidopsis multilocus ; Bioindicators
Library Call Number Additional Info Location Last
NTIS  PB84-182195 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 33p
The paper compares the sensitivity, specificity and accuracy of Arabidopsis multilocus assay with several other in vitro and in vivo bioassays. Sensitivity was defined as a percentage of the carcinogens correctly identified as mutagens. Specificity was calculated by multiplying with 100 the fraction of the number correctly identified 'non-carcinogens'/total number of 'non-carcinogens' unambiguously classified. Accuracy represents the fraction of the correct answers/all unambiguous test, multiplied with 100. These parameters were estimated in Arabidopsis by testing 37 carcinogen/non-carcinogen pairs of chemicals. The overall sensitivity of Arabidopsis assay was higher than any of the bioassays employed in the Internation Collaborative Program.