Record Display for the EPA National Library Catalog


Main Title Toxic effects of xenobiotics on the pituitary gland. {microfiche}
Author Walker, R.F. ; Cooper., R. L.
CORP Author Smith Kline Beecham Corp., King of Prussia, PA. Dept. of Toxicology.;Health Effects Research Lab., Research Triangle Park, NC. Toxicology Branch.
Publisher Smith Kline Beecham for US Environmental Protection Agency,
Year Published 1991
Report Number EPA/600/D-90/198
Stock Number PB91-136903
Additional Subjects Toxicity ; Pituitary gland ; Metals ; Reproduction(Biology) ; Homeostasis ; Estrogen ; Pesticides ; Hypothalamus ; Pituitary neoplasms ; Xenobiotics ; Toxic substances ; Monoamines ; Carcinogenicity tests
Library Call Number Additional Info Location Last
NTIS  PB91-136903 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 55 p. ; 28 cm.
The document provides a summary of adverse effects of xenobiotics upon the pituitary gland, an endocrine gland that plays an important role in the regulation of reproductive function. The most common histopathological pituitary lesions observed following exposure to drugs and chemicals are reviewed along with the potential consequences of these lesions on physiological function and the maintenance of homeostasis. In addition, other mechanisms involved in the alteration of pituitary function are discussed. These include changes in function that occur in response to a toxicant's effect on the central nervous system or target gland and thus indirectly influence pituitary gland activity.
"EPA 600/D-90/198."