Record Display for the EPA National Library Catalog


Main Title Letter from Chemical Manufacturers Assoc to Usepa Regarding Enclosed Materials Presented at 091086 Public Meeting with Chemical Manfacturers Assoc & Eastman Kodak Co W-attached.
CORP Author Chemical Manufacturers Association, Washington, DC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number 40-8699090
Stock Number OTS0525397
Additional Subjects Toxicology ; Health effects ; Triethylene Glycol Ethers ; Pharmaco Kinetics ; Mammals ; Humans ; In Vitro ; Subchronic Toxicity ; Rabbits ; Dermal ; Reproduction/fertility Effects ; Teratogenicity ; Rats ; Oral ; Gavage ; Toxic substances ; Laboratory animals ; CAS No 109-86-4 ; CAS No 110-80-5 ; CAS No 111-76-2 ; CAS No 111-77-3 ; CAS No 111-90-0 ; CAS No 112-34-5 ; CAS No 112-35-6 ; CAS No 112-50-5 ; CAS No 143-22-6
Library Call Number Additional Info Location Last
NTIS  OTS0525397 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 20p
Summary toxicokinetic and toxicity information regarding glycol ethers is presented. Comparitive absorption rates of glycol ethers through human epidermis in vitro ranged from 22.2 ug/sq cm/hr (for triethylene monobutyl ether) to 2705 ug/sq cm/hr (for ethylene monomethyl ether). In a dermal limit test with rabbits, each glycol ether was administered at 1 g/kg under occlusion to shaved backs of rabbits for 6 hrs/day, 5 days/week for 3 weeks. No toxic effects were noted other than irritation at the site of application. CMA briefly outlined a proposed subchronic dermal toxicity study of triethylene glycol methyl ether with rabbits.