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RECORD NUMBER: 21 OF 24

Main Title Summary Results of Research Directed Toward Eliciting Effects of Exposure to Carbon Monoxide on the Spontaneous Electroencephalogram and Visual Evoked Cortical Electrical Activity.
CORP Author Medical Coll. of Wisconsin, Milwaukee. Dept. of Environmental Medicine.;Coordinating Research Council, Inc., New York.;Environmental Protection Agency, Washington, D.C.
Year Published 1974
Report Number MCOW-ENVM-CO-74-3; APRAC-CAPM-3-68; CRC-APRAC-CAPM-3-68-7;
Stock Number PB-242 202
Additional Subjects Carbon monoxide ; Electroencephalography ; Air pollution ; Exposure ; Central nervous system ; Electrophysiology ; Brain ; Humans ; Visual evoked response ; Air pollution effects(Humans) ; Carbonylhemoglobin
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  PB-242 202 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 36p
Abstract
The spontaneous electroencephalogram (EEG) and the visual evoked cortical electrical activity (visual evoked response, VER) were studied in young adult males to ascertain the effects of exposure to carbon monoxide (CO). The EEG was found to be generally resistant to change during eight hours of exposure at the lower CO concentrations (maximum carboxyhemoglobin saturations of 10 and 22 percent). During the eight hour exposures, the VER was generally resistant to change until COHb levels of 22 percent were achieved, while with 24 hours of exposure changes were evident even at the lowest concentrations (COHb equals 4-10 percent). This change, an increase in VER wave amplitude, suggest that these exposures induced central nervous system depression.