Record Display for the EPA National Library Catalog

RECORD NUMBER: 125 OF 308

Main Title Initial Submission: Primary Skin Irritation of Para Toluene Sulfonic Acid in Humans with Cover Letter dated 08/07/1992.
CORP Author Product Investigations, Inc.; Monsanto Chemical Co., St. Louis, MO.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1992
Report Number 8EHQ-0892-10286
Stock Number OTS0570868
Additional Subjects Toxicology ; Health effects ; Toxic substances ; Para toluene sulfonic acid ; Primary dermal irritation ; Mammals ; Humans ; Dermal ; CAS No 104-15-4
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  OTS0570868 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 48p
Abstract
The procedure was a single-blind evaluation in a randomly selected group of panelists from a local institution. The test material was one of several being evainated concurrently on the members of this panel. Each concentration of the test material was assigned a distinct and separate contact site on each panelist for a series of four (4) consecutive twenty-four-hour applications. Starting with the 6.25% concentration, each incremental concentra- tion was to be phased into the study at twenty-four-hour intervals if the skin proved tolerant to the lower concentrations. If the 6.25% concentration proved to be too irritating, a 1% concentration was started, to be followed by 2% and 3% concentrations.