Record Display for the EPA National Library Catalog


Main Title High Resolution of Mouse Chromosomes: Banding Conservation between Man and Mouse (Journal Version).
Author Sawyer, J. R. ; Hozier, J. C. ;
CORP Author Florida Inst. of Tech., Melbourne.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher c1986
Year Published 1986
Report Number EPA-R-812163; EPA/600/J-86/488;
Stock Number PB89-105381
Additional Subjects Evolution ; Mice ; Chromosome banding ; Cytogenetics ; Chromosomes ; Prophase ; Genetics ; Inbred DBA mice ; Laboratory animals ; Humans ; Chromosome mapping ; Reprints ;
Library Call Number Additional Info Location Last
NTIS  PB89-105381 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 5p
A detailed schematic representation of high resolution G-banding patterns was prepared from elongated and finely banded mitotic chromosommes of the mouse. Such chromosomes can be obtained from both animal tissue and cell lines by a simple protocol, facilitating precise demarcation of break points in chromosome rearrangements, as well as aiding in sublocalization of genes. Regions of subbanding homology were observed between human and mouse chromosomal segments known to have conserved gene assignments indicating that, at the cytogenetic level, extensive regions of the mammalian genome may remain intact after 60 million years of species divergence. (Copyright (c) 1986 by the American Association for the Advancement of Science.)